Iyini i-PLLA (i-Poly-l-lactic Acid)?

Iyini i-PLA?

Ngokuhamba kweminyaka, ama-polymers e-lactic acid asetshenziswe kabanzi ezinhlotsheni ezihlukene zemikhakha yezokwelapha, njengalezi: ama-sutures adonsayo, izimila ze-intraosseous kanye nokufakelwa kwezicubu ezithambile, njll., kanye ne-poly-L-lactic acid iye yasetshenziswa kabanzi eYurophu ukwelapha ubuso. ukuguga.

Ihluke ezintweni zokugcwalisa izimonyo ezaziwa kakhulu njenge-hyaluronic acid, i-allogeneic collagen namafutha e-autologous, i-PLLA (i-poly-L-lactic acid) ingeyesizukulwane esisha sezinto zokuvuselela zezokwelapha.

Kuyimpahla yezokwelapha eyenziwe umuntu engabola futhi imunce, inokuvumelana okuhle kwe-biocompatibility kanye nokuwohloka, futhi ingabola ibe isikhutha kanye namanzi ngokwawo emzimbeni.

I-PLLA isetshenziswe kabanzi emkhakheni wezokwelapha cishe iminyaka engu-40 ngenxa yokuphepha kwayo, futhi ngemva kokusetshenziswa emkhakheni wobuhle bezokwelapha, ithole amalayisense ngokulandelanayo kuma-ejensi alawulayo anegunya emazweni amaningi:

1. Ngo-2004, i-PLLA yagunyazwa e-Europe yokwelapha i-lipoatrophy enkulu yobuso.

2. Ngo-Agasti 2004, i-FDA yagunyaza i-PLLA ukuthi ijovwe ukwelapha i-atrophy ebusweni ehlobene nokutheleleka nge-HIV.

3. NgoJulayi 2009, i-FDA yagunyaza i-PLLA ukuze kube nokugoqeka kwe-nasolabial okuthambile kuya kokuqina, ukonakala kobuso obuqinile kanye neminye imibimbi yobuso ezigulini ezinempilo.

Izimbangela zokuguga

Isikhumba sesikhumba sakhiwe yi-collagen, elastin, kanye ne-glycosamine substances,i-collagen yenza ngaphezu kwama-75%, futhi iyingxenye eyinhloko yokugcina ukujiya kwesikhumba nokunwebeka kwesikhumba.

Ukulahleka kwe-collagen kuyisizathu esiyinhloko sokuphuka kwenethiwekhi enwebekayo esekela isikhumba, ukushwabana nokuwa kwezicubu zesikhumba, kanye nokubonakala kwezinto ezomile, ezimahhadlahhadla, ezixegayo, ezishwabene nezinye esikhumbeni!

I-collagen eyanele ingenza amangqamuzana esikhumba agcwale, enze isikhumba simanzi, sithambile futhi sishelele, futhi kuvimbele ngempumelelo isikhumba ukuguga.

I-PLA ingahlangabezana nesidingo sesikhumbaukuvuselelwa kwe-collagen. Inomphumela wokukhushulwa obaluleke kakhulu ezingeni lokukhula kwe-collagen, futhi ingafinyelela ukukhula okusheshayo kwe-collagen density esikhumbeni ngesikhathi esifushane, futhi uyigcine isikhathi eside.ngaphezu kweminyaka emi-2.

I-PLA ingathuthukisa ngempumelelo ukuzilawula kwesikhumba, ukukhanda nokuvuselela imisebenzi ngokukhuthaza ukuvuselelwa kwe-collagen ne-elastin, ukwelula ukuthungwa.

Rarulula inkinga yokuntuleka komswakama ku-dermis nokulahlekelwa kwe-collagen ezimpandeni, yenza amangqamuzana esikhumba agcwale, futhi isikhumba sibuyele esimweni esifanele somswakama ogcwele, obucayi futhi obushelelezi.

Icala lokwelashwa langempela